Symmetrical progressive erythrokeratoderma

Synonym:

Gottron's syndrome

Symmetrical progressive erythrokeratoderma is an autosomal dominant disorder characterized by large, slightly elevated red to red-yellow, sharply demarcated plaques with a fine scale.
Lesions are usually symmetrical and can expand peripherally.

Treatment:

• Spontaneous clearing in sporadic cases has been reported.
• PUVA, etretinate, and acitretin have all been reported to be effective.
• Long term treatment is usually required.

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