Variegate porphyria

Variegate porphyria, inherited as an autosomal dominant trait, has skin changes indistinguishable from porphyria cutanea tarda. In addition, patients with variegate porphyria have systemic complaints more typical of acute intermittent porphyria.

Treatment:

• Treatment of the systemic symptoms of variegate porphyria is identical for that acute intermittent porphyria.
• Skin lesions are managed in a similar way to those of porphyria cutanea tarda patients.

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