Streptomycin

Streptomycin, in combination with other agents, is useful in the treatment of tuberculosis, mycetoma, and other infections with sensitive organisms.

Precautions:

• The risk of neurotoxicity is increased if there is renal impairment.
• Many drug interactions - see your compendium.

Adverse effects:

• Ototoxicity - nausea, vomiting, vertigo, deafness.
• Urticaria and other skin reactions.

Dosage:

• Typical dosage is 1 to 2 gm/day, intramuscularly.

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