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Sarcoidosis

Sarcoidosis is a disease of unknown etiology characterized in the skin by red to violaceous papules and plaques with a granulomatous histology.
There is a tendency to systemic involvement with restrictive pulmonary disease and ocular involvement being common.
Skin disease shows many patterns including:

Lupus pernio:

violaceous plaques involving the nose, central face, and ears.

Scar sarcoidosis:

sarcoid skin lesions with a predilection to scars.

Papular sarcoidosis:

grouped red-brown papules, most common on the face and limbs.

Nodular sarcoidosis:

lesions are larger than papules and can tend to form plaques.

Erythema nodosum is a common presenting sign of sarcoidosis. Sarcoidosis is more common in African-Americans than in whites.

Treatment:

  • Chloroquine and hydroxychloroquine maybe effective
  • Thalidomide can also be considered
sarcoidosis


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