Hives, or urticaria, is an allergic disorder characterized by raised and usually itchy welts on the skin surface. There are different causes of hives, and the treatment for it varies depending on its cause. Identifying its specific cause, such as food or a certain medication, will help you in preventing its future occurrence by just simply avoiding exposure to the cause.

The good thing about hives is that most of its forms are mild and resolve on their own. However, there are severe forms of hives that could be life threatening and do not resolve on their own. Therefore, the rule of thumb is to consult your doctor at once if you suddenly have an attack of hives, in order to receive immediate and appropriate treatment. Do this especially if you are pregnant, or have other comorbidities such as hypertension, recurrent hives lasting more than or equal to a month, or hives accompanied by nausea, dizziness, cough, difficulty in breathing and cold sweats.

H1 Antihistamines

Histamines are the main culprit for producing the symptoms of hives. Antihistamines work by blocking the effects of histamines, and this makes them effective in relieving symptoms of hives. Antihistamines are drugs that are taken orally. They are the drugs of choice for most forms of hives. There are two classes of H1 antihistamines: first generation or the sedating class, and second generation or the non-sedating class. The second-generation H1 antihistamines are less likely to cause drowsiness than the first generation.

First-generation antihistamines include chlorpheniramine, diphenhydramine and hydroxyzine. Chlorpheniramine and diphenhydramine are over-the-counter medications, while hydroxyzine is a prescription medication. Aside from drowsiness, their other side effects include dry mouth, blurring of vision, constipation and difficulty in urinating. First-generation antihistamines are deemed more beneficial than second-generation antihistamines because they do not respond well to the pharmacological effects of the latter.

Loratadine, cetirizine, desloratadine and fexofenadine belong to the second-generation antihistamines. The first two are over-the-counter medications, while the last two are prescription medications. Doctors often prescribe these drugs because they do not cause significant drowsiness that may impair or hinder daily functional activities.

Other Medications

There are effective drugs that can be used or added in conjunction with antihistamines if these have been inadequate. These drugs include H­2 antagonists (such as cimetidine, ranitidine and famotidine), tricyclic antidepressants (such as doxepin), leukotriene receptor antagonists (such as montelukast and zafirlukast), oral and systemic steroids, and cyclosporine.

H­2 antagonists such as tricyclic antidepressants and leukotriene receptor antagonists serve as add-on therapy to antihistamines. Oral steroids can also help in symptom relief, but prolonged use of these drugs may cause serious side effects. Systemic steroids are helpful in the treatment of severe forms of hives. Cyclosporines are effective for forms of hives that are severe, chronic and poorly responsive to other treatments.

Home Remedies

You can prepare a soothing bath by adding oatmeal (5 or 6 tbsp.) and cornstarch or sodium bicarbonate (3 tbsp.) to your bath water. You can also ask your doctor to prescribe you with an emergency kit for hives that contains epinephrine.