Typically developing after the primary chancre has faded, secondary syphilis is manifested by a macular or maculopapular eruption which covers much of the body surface including palms and soles.
Skin lesions may be evanescent or fixed. Lesions typically show a superficial scale, but a papular variant can also occur and consists of diffuse 2 to 4 mm red-brown papules over the body surface.
Genital or perianal papules that become verrucous are called condylomata lata.
A patchy alopecia can occur.
There may be low grade systemic symptoms.
- Lesions fade without treatment, but treatment is still necessary to prevent the stigmata of late syphilis.
- See: Syphilis for treatment details.