Nasal scrapings - leprosy
Nasal scrapings are used to assess treatment response in patients with lepromatous, or near lepromatous leprosy. A curette is used to scrape the posterior nasal septum. The curette is inserted 4 to 6 cm. The scrapings are then spread on a glass slide, fixed, and assessed for acid-fast bacilli.
As nasal scrapings become negative earlier with treatment, slit smears are the preferred monitoring test.