Lupus erythematosus profundus

Lupus erythematosus profundus

Synonym:

Lupus panniculitis

LE profundus is a panniculitis associated with both discoid and systemic lupus erythematosus.
Firm nodules up to several centimeters are noted involving the subcutaneous skin. These lesions can heal, resulting in a depression.

Treatment:

  • Intralesional injections of triamcinolone 5-10 mg/ml may be helpful.
  • Systemic anti-malarial agents such as hydroxychloroquine 400 mg bid may be needed.
lupus erythematosus profundus

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