Chloroquine phosphate (Aralen?) is used to treat progressive cutaneous lesions of systemic lupus erythematosus or discoid lupus erythematosus resistant to topical or intralesional glucocorticoids.
- Pregnancy is a relative contraindication.
- Irreversible dose related retinal damage can occur. Retinal function, including visual fields, must be monitored at 3 month intervals during long term therapy.
- A typical dosage is 250 mg po daily.